HOME ABOUT US PRINT PUBLICATIONS SUBSCRIPTIONS CONTACT US RSS
 
Subscriber Sign In
 
Today@FDA
FDA Calendar
 
Archived Daily Updates
 
FDA Whistleblower
 
What do you think?
Search our 63,616-story database
Search
Renew subscription










E-mail This to a Friend | Print Format  
     
 
Draft Guide on Cadmium Elemental Impurities Q3D
07/13/2018
 

FDA has posted a draft guide from the International Council for Harmonization on “Elemental Impurities Q3D(R1).” The document discusses cadmium and how it has been shown to be genotoxic, but not mutagenic and has been acknowledged as a human carcinogen. Also, positive associations have been observed between exposure to cadmium and cadmium compounds and cancer of the kidney and of the prostate, the guidance says. “A sensitive endpoint for oral exposure to cadmium and cadmium salts is renal toxicity,” it adds. “Skeletal and renal effects are observed at similar exposure levels and are a sensitive marker of cadmium exposure.”


Post an instant comment on this report here

 
Any copying or electronic transfer without written permission is strictly prohibited and will result
in termination of service and prosecution under the federal Copyright Act.
To gain permission to copy this article log on to http://www.copyright.com.

FERDIC INCORPORATED - P.O. Box 28, Camp Hill, PA 17001 | Phone: (717)731-1426 fax:(717)731-1427 Email: info@fdaweb.com