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FDA releases a corrected version of a 12/30 Complete Response Letter issued to Corcept Therapeutics, indicating that the agency had repeatedly warned the company against submitting its NDA for relacorilant.

latest-news

FDA discontinues the use of its Quality System Inspection Technique for medical device inspections and will instead conduct inspections using the process described in the updated Inspection of Medical Device Manufacturers Compliance Program (CP 7382.850).

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FDA Releases Corrected Rejection Letter for Corcept NDA

FDA releases a corrected version of a 12/30 Complete Response Letter issued to Corcept Therapeutics, indicating that the agency had repeatedly warned the company against submitting its NDA for relacorilant.

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FDA Updates Device Inspection Program Due to QMSR Move

FDA discontinues the use of its Quality System Inspection Technique for medical device inspections and will instead conduct inspections using the process described in the updated Inspection of Medical Device Manufacturers Compliance Program (CP 7382.850).

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Senators Question HHS Oversight of TrumpRx Platform

A group of Democratic senators ask HHS’ Office of Inspector General to clarify how it will oversee direct-to-consumer prescription drug sales tied to the forthcoming TrumpRx Web site, raising concerns about potential violations of federal fraud and abuse laws.

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Sen. Scott Bill to Require Country-of-Origin on Rx Labels

Sen. Rick Scott (R-FL) introduces legislation that would require prescription drug labels in the U.S. to disclose where drugs and their active pharmaceutical ingredients are manufactured.

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Animal Drugs

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medical-devices
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Sydnexis Pediatric Myopia Drug Meets Endpoints

Sydnexis says its SYD-101 drug to treat pediatric progressive myopia met both the primary and key secondary endpoints in the Phase 3 STAR trial.

medical-devices
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10/9 Vaccines Panel to Recommend Flu Strain Selection

FDA schedules a 10/9 Vaccines and Related Biological Products Advisory Committee meeting to make recommendations on the strain selection for influenza...

medical-devices
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Capsida Pauses Gene Therapy Trial After Death

Capsida Biotherapeutics stops enrollment in its SYNRGY clinical trial that is evaluating gene therapy CAP-002 for treating STXBP1 developmental and ep...

medical-devices
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Guide on Biosimilar Formal Meeting Requsts

FDA releases a final guidance entitled Formal Meetings Between the FDA and Sponsors or Applicants of BsUFA Products.

Biologics

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medical-devices
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Kennedy Ally Says Makary Blocking Covid Shot Withdrawal

Axios reports that the vice chair of the CDC Advisory Committee on Immunization Practices says the Pfizer and Moderna Covid mRNA vaccines should be re...

medical-devices
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Summit BLA for Lung Cancer Therapy

FDA accepts for review a Summit Therapeutics BLA seeking approval for ivonescimab in combination with chemotherapy in patients with epidermal growth f...

medical-devices
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2 Regenxbio Gene Therapies Get Clinical Holds

FDA places clinical holds on two Regenxbio investigational gene therapy programs for ultra-rare pediatric diseases following the identification of a c...

medical-devices
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Sarepta Reports Positive Data on Duchenne Gene Therapy

Sarepta Therapeutics announces that its gene therapy Elevidys significantly slowed disease progression over three years in ambulatory patients with Du...

FDA General

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medical-devices
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Symposium on Clinical Trials, Bioequivalence and Pharmacovigilance

U.S., U.K. and Canadian drug regulators announce a joint international symposium to discuss evolving regulatory expectations for clinical trials, bioe...

medical-devices
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Pazdur Warns About Political Interference, Upheaval At FDA

Former FDA Oncology Center for Excellence director Richard Pazdur warns that political interference and internal upheaval are eroding the agency’s abi...

medical-devices
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Harvard Law Hits User Fees Over ‘Corporate Capture’

A new analysis from Harvard Law School argues that the U.S. drug regulator’s reliance on industry-paid user fees has left the agency vulnerable to bot...

medical-devices
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End-of-December Warning Letters

FDA releases substantive Warning Letters in the last two weeks of December 2025.

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Federal Register

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PDUFA Public Meeting for User Fee Reauthorization

Federal Register notice: FDA announces a 7/14 public meeting to discuss proposed recommendations for...

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Generic Drug Fee Program Reauthorization Meeting

Federal Register notice: FDA hosts a 7/11 public meeting on the reauthorization of the Generic Drug ...

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FDA Withdraws and Reissues 2 Guidances

FDA says it is withdrawing two recent final guidances on cell- and tissue-based products and reissui...

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CDER Continues Quality Management Program

Federal Register notice: FDA seeks drug manufacturing establishments to participate in the second ye...

Human Drugs

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FDA Releases Corrected Rejection Letter for Corcept NDA

FDA releases a corrected version of a 12/30 Complete Response Letter issued to Corcept Therapeutics,...

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Read More
Senators Question HHS Oversight of TrumpRx Platform

A group of Democratic senators ask HHS’ Office of Inspector General to clarify how it will oversee d...

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Read More
Sen. Scott Bill to Require Country-of-Origin on Rx Labels

Sen. Rick Scott (R-FL) introduces legislation that would require prescription drug labels in the U.S...

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Ultragenyx Resubmits BLA for Gene Therapy

Ultragenyx Pharmaceutical resubmits a BLA seeking accelerated approval for UX111, an AAV9 gene thera...

Marketing

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Neffy Broadcast Ad ‘False or Misleading’: OPDP

An FDA Untitled Letter cautions ARS Pharmaceutical about false or misleading claims for its Neffy na...

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Cobenfy Ad Letter Signals Tight Limits on DTC Claims: Attorneys

A December FDA violation letter targeting a schizophrenia drug advertisement from Bristol Myers Sq...

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FDA Flags AstraZeneca’s Farxiga TV Ad as Misleading

FDA cites a direct-to-consumer television advertisement for AstraZeneca’s Farxiga (dapagliflozin) ta...

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Oversight of Influencer Social Media Posts Hard: Researchers

University of Chicago researchers explain how difficult it will be to improve government oversight o...

Medical Devices

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FDA Updates Device Inspection Program Due to QMSR Move

FDA discontinues the use of its Quality System Inspection Technique for medical device inspections a...

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Grail Submits Final PMA Module for Cancer Blood Test

Grail files the final module of its PMA for the company’s multi-cancer early detection blood test.

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Agency Clarifies Clinical Decision Support Software

FDA posts an updated guidance clarifying when clinical decision support software functions fall outs...

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FDA Annual Report on CDRH International Harmonization

CDRH reports on its 2025 MDUFA 5 activities to promote international harmonization.