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Human Drugs

Ortho Regenerative Submits Response to Ortho-R Clinical Hold

Ortho Regenerative Technologies says it has submitted information requested by FDA to resolve a clinical hold on the Ortho-R drug/biologic combination...

FDA General

Domestic Inspections Resume Standard Operations

FDA acting commissioner Janet Woodcock says that beginning this month, FDA started transitioning back to standard operations for domestic inspections.

Human Drugs

FDA Approves Mercks Pneumococcal Vaccine

FDA approves Mercks Vaxneuvance (pneumococcal 15-valent conjugate vaccine) for active immunization for preventing invasive disease caused by 15 Strept...

Human Drugs

FDA Accepts Aquestive NDA Resubmission

FDA accepts for review an Aquestive Therapeutics NDA resubmission for Libervant (diazepam) Buccal Film for managing seizure clusters.

Human Drugs

Expanded Use of Prograf Relied on RWE

FDA approves a new use for Astellas Pharmas Prograf (tacrolimus), based on real-world, for use in combination with other immunosuppressant drugs to pr...

Human Drugs

Shift to Include Pregnant Women in Trials: FDA

FDA pushes for a major paradigm shift to move the clinical development community from systemic exclusion to the inclusion of pregnant and breastfeedin...

Medical Devices

Aortic Aneurysm Device is Breakthrough

FDA grants Endologix a breakthrough device designation for its ChEVAS (Chimney EndoVascular Aneurysm Sealing) System, an endovascular abdominal aortic...

Human Drugs

Ardelyx Tenapanor NDA Hits FDA Snag

Ardelyx says FDA found deficiencies in the NDA review for tenapanor that preclude discussion of labeling and post-marketing requirements/commitments a...

Medical Devices

Nevro OKd for Treating Diabetic Neuropathy

FDA approves a Nevro Corp. PMA for its Senza System for treating chronic pain associated with painful diabetic neuropathy.

Federal Register

Latest Federal Register Notices

FDA Review posts the Federal Regiter notices for the week ending 7/16/2021.