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Human Drugs

FDA Clinical Hold on Protagonist Rusfertide Studies

FDA places a clinical hold against three Protagonist Therapeutics clinical studies for rusfertide due to concerning mouse study findings.

Medical Devices

Study Looks at FDA Regulation of Laboratory-Developed Tests

Massachusetts General Hospital researchers say FDA policy deviations for regulatory laboratory-developed tests during the Covid-19 pandemic give a clu...

Human Drugs

Clozapine REMS Changes Effective 11/15

FDA says changes to the clozapine REMS to ensure that the drugs benefits outweigh the risk of severe neutropenia take effect 11/15.

Biologics

Moderna Says Data Support Booster Shot

Moderna says an analysis of a Phase 3 study of its Covid-19 mRNA vaccine supports the usefulness of a booster shot.

Federal Register

Revised Guide on Ferric Oxyhydroxide ANDAs

Federal Register notice: FDA makes available a revised draft guidance for industry entitled Draft Guidance for Ferric Oxyhydroxide.

Federal Register

Info Collection on Biosimilar User Fees

Federal Register notice: FDA seeks comments on an information collection revision entitled Biosimilars User Fee Program.

Human Drugs

AbbVie Files Rinvoq sNDA for Ulcerative Colitis

AbbVie files a supplemental BLA for Rinvoq (upadacitinib) for treating certain adults with moderately to severely active ulcerative colitis.

Human Drugs

FDA Approves Takedas Exkivity for Some Lung Cancers

FDA approves Takedas Exkivity to treat specified non-small cell lung cancer patients identified that an approved diagnostic test.

Human Drugs

ICH Guidance Combined: Validation of Analytical Procedures

FDA says it has consolidated two ICH guidances and retitled them Q2(R1) Validation of Analytical Procedures: Text and Methodology.

Marketing

FDA Releases Bad Ad Quiz

FDA releases a quiz that participants can use to determine how much they know about prescription drug promotion and the Bad Ad program.