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Biologics

Eisai Rolling BLA for Alzheimers Drug

Eisai begins a rolling BLA submission for lecanemab, the companys investigational anti-amyloid beta protofibril antibody for treating early Alzheimers...

Human Drugs

Pfizer Amends Trial Protocol Due to Adverse Events

Pfizer submits a clinical trial protocol amendment for a Phase 3 gene therapy trial for fordadistrogene movaparvovec in Duchenne Muscular Dystrophy pa...

Federal Register

Workshop on Analgesic Clinical Trial Designs

Federal Register notice: FDA announces a 10/13-14 public workshop entitled Analgesic Clinical Trial Designs, Extrapolation, and Endpoints in Patients ...

Human Drugs

Lilly Recalls 1 Lot of Glucagon Emergency Kit

Eli Lilly recalls one lot of its Glucagon Emergency Kit for Low Blood Sugar after receiving a product complaint reporting that a vial of glucagon was ...

Human Drugs

BMS Files 2 sBLAs for Opdivo/Yervoy

FDA accepts for review two Bristol Myers Squibb supplemental BLAs for Opdivo (nivolumab) in combination with Yervoy (ipilimumab) and Opdivo in combina...

Human Drugs

FDA and UK Expand Mutual Recognition Agreement

FDA and the United Kingdom expand their ongoing mutual recognition agreement to include animal drug inspections.

Medical Devices

Alert on Left Atrial Appendage Occlusion Devices

FDA alerts health care providers on recent information about the potential for differences in procedural outcomes between women and men undergoing imp...

Human Drugs

CDER Head Talks Quality Management Maturity

CDER director Patrizia Cavazzoni tells an industry conference that agency inspectors are emphasizing the importance of having in place effective risk-...

Medical Devices

Enforcement Discretion for Certain IVD Studies

FDA says it intends to exercise enforcement discretion regarding a requirement for informed consent for in vitro diagnostic device studies using lefto...

Human Drugs

Clinical Hold Lifted on Angelman Syndrome Study

FDA removes a clinical hold against a GeneTx Biotherapeutics and Ultragenyx Pharmaceutical clinical trial of GTX-102, an investigational treatment for...