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Biologics

Immunocore BLA for Melanoma Approved

FDA approves an Immunocore BLA for Kimmtrak (tebentafusp-tebn) for treating certain adult patients with unresectable or metastatic uveal melanoma.

Human Drugs

Gilead Partial Clinical Hold on Magrolimab Trials

FDA places a partial clinical hold on Gilead Sciences studies evaluating the combination of magrolimab plus azacitidine (Celgenes Vidaza) due to an ap...

Human Drugs

CGMP Deviations at Aurobindo Facility

FDA warns Aurobindo Pharmaceutical about repeat CGMP deviations in the manufacturing of active pharmaceutical ingredients at its plant in Doultabad, T...

Biologics

Dissident FDA Vaccines Deputy Joins Adjuvance Technologies

Former dissident CBER Office of Vaccines Research and Review deputy director Philip Krause joins Adjuvance Technologies as a strategic consultant.

Medical Devices

Medical Device Study Patient Engagement Guidance

FDA publishes a guidance on using patient engagement to support the design and conduct of medical device clinical studies.

Human Drugs

Vaccines Panel Meets to Pick Flu Vaccine Strains

Federal Register notice: FDA announces a 3/3 Vaccines and Related Biological Products Advisory Committee meeting that will select strains to be includ...

Biologics

CBER Plans 13 Guidances in 2022

CBER releases a list of 13 guidances it is considering developing in 2022.

Human Drugs

Soleno Needs Another Trial for NDA Filing: FDA

FDA tells Soleno Therapeutics that an additional clinical trial is necessary before the company submits an NDA for once-daily DCCR (diazoxide choline)...

Human Drugs

Pfizer/BioNTech Begin Omicron Vaccine Study

Pfizer and BioNTech begin a clinical study to evaluate the safety, tolerability and immunogenicity of an Omicron-based vaccine candidate.

Medical Devices

Medical Device PRO Guidance

FDA publishes a guidance on using patient-reported outcome instruments in medical device evaluation.