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Federal Register

Guide on Rescinding Breakthrough Therapy Designations

Federal Register notice: FDA makes available a draft guidance entitled Considerations for Rescinding Breakthrough Therapy Designation.

Federal Register

Drug GMP Guide on Preventing Cross-Contamination

Federal Register notice: FDA makes available a draft guidance entitled Non-Penicillin Beta-Lactam Drugs: A CGMP Framework for Preventing Cross-Contami...

Federal Register

Guide on Food Effect Clin-Pharm Considerations

Federal Register notice: FDA makes available a final guidance entitled Assessing the Effects of Food on Drugs in INDs and NDAs Clinical Pharmacology ...

Human Drugs

Guide on Oligonucleotide Therapeutic Development

FDA makes available a draft guidance entitled Clinical Pharmacology Considerations for the Development of Oligonucleotide Therapeutics.

Human Drugs

AbbVie sNDA for Qulipta to Prevent Chronic Migraine

AbbVie submits an sNDA for Qulipta as a preventive treatment for chronic migraine.

Federal Register

Info Collection on 510(k) 3rd-Party Review Program

Federal Register notice: FDA seeks comments on an information collection extension entitled 510(k) Third-Party Review Program (OMB Control Number 0910...

Federal Register

Info Collection on Device Registration/Listing

Federal Register notice: FDA sends to OMB an information collection extension entitled Establishment Registration and Device Listing for Manufacturers...

Explain Need for Trial Diversity: Caplan

New York University bioethicist Arthur Caplan says those calling for greater diversity in clinical trials should clearly explain the benefits of such ...

Human Drugs

FDA 5-Year Plan to Treat Diseases Like ALS

FDA issues a five-year action plan for fostering and advancing drug development for rare neurodegenerative diseases such as ALS.

Human Drugs

Accelerated Approval for Novartis Combo Therapy

FDA grants Novartis accelerated approval for Tafinlar (dabrafenib) plus Mekinist (trametinib) for treating certain patients six years of age and older...