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Biologics

Pfizer Seeks Covid Vaccine EUA for Children 5-12

Pfizer and BioNTech say they have formally submitted an emergency use authorization request for their mRNA Covid-19 vaccine and its use in children ag...

Medical Devices

FDA Reclassifies Surgical Staplers, Staples

FDA reclassifies surgical staplers for internal use from Class 1 to Class 2 and delays enforcement of the change for 180 days.

Human Drugs

De Novo Sought for Fibromyalgia Neuromodulator

NeuroMetrix submits a de novo request for its Quell wearable neuromodulation device for treating symptoms of fibromyalgia in adults.

Human Drugs

Hospital, Health System Drug Compounding Guidance

FDA issues a revised draft guidance on drug compounding by hospital and health system pharmacies.

Polarean Imaging Complete Response Letter

FDA raises issues to be resolved in a complete response letter to a Polarean Imaging NDA for a drug-combination product to enhance MRI imaging in pulm...

Federal Register

Guide on Real-world Data for Animal Drug

Federal Register notice: FDA makes available a final guidance entitled #266 Use of Real-World Data and Real-World Evidence to Support Effectiveness of...

Federal Register

Guide on Foreign Studies for Animal Drugs

Federal Register notice: FDA makes available a final guidance entitled #265 Use of Data from Foreign Investigational Studies to Support Effectiveness ...

Human Drugs

Cassava Sciences Opens Phase 3 Alzheimers Trial

Cassava Sciences says it is opening its first of two Phase 3 efficacy studies of simufilam for use in patients with mild to moderate Alzheimers diseas...

Human Drugs

FDA Benefit/Risk Guidance Analyzed

Fagere Drinker consultants analyze a new FDA draft guidance on how the agency handles benefit/risk assessment for drug and biological products.

Human Drugs

Acer NDA for Urea Cycle Disorders

FDA accepts for review an Acer Therapeutics NDA for Acer-001 sodium phenylbutyrate) for treating patients with urea cycle disorders.