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Biologics

High Immune Response in Pfizer Booster in Kids

Pfizer says it and BioNTech will request an FDA emergency use authorization for a Covid vaccine booster shot for children ages 5-11.

Human Drugs

NDA, IND Bioavailability Studies Guidance

FDA publishes a guidance to help sponsors submit bioavailability information for specified drug products in INDs and NDAs.

Federal Register

Draft Guide on Trial Diversity Plans

Federal Register notice: FDA makes available a draft guidance entitled Diversity Plans to Improve Enrollment of Participants from Underrepresented Rac...

Massive Judgment Against Ethicon Upheld

A California appeals court upholds $302 million of a $344 million trial court judgment against Ethicon over misleading communications about its pelvic...

Human Drugs

FDA Breakthrough Rescission on Protagonists Rusfertide

FDA tells Protagonist Therapeutics that it intends to rescind the companys breakthrough therapy designation for rusfertide and its use in treating pol...

Biologics

Merck Gets Breakthrough on Pneumococcal Vaccine

FDA grants Merck a breakthrough therapy designation for V116, an investigational 21-valent pneumococcal conjugate vaccine.

Human Drugs

AbbVie, Genmab Contacting Regulators on Cancer Drug

AbbVie and Genmab say they will open regulatory discussions on their investigational cancer drug epcoritamab, based on Phase 1/2 trial topline results...

New Guidance Promotes More Trial Diversity

FDA publishes a draft guidance updating a 2016 guidance by telling medical product sponsors what should be included in a Race and Ethnicity Diversity ...

Human Drugs

House Committee Releases McKinsey Report

The House Committee on Oversight and Reform issues a report demonstrating McKinsey & Companys conflicts of interest in working for opioid manufacturer...

Human Drugs

pH Adjuster Waiver Request Guidance

FDA publishes a draft guidance to help ANDA applicants prepare and submit pH adjuster waiver requests for specific types of drugs.