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Federal Register

Guide on Real-World Data Use in Submissions

Federal Register notice: FDA posts a draft guidance entitled Considerations for the Use of Real-World Data and Real-World Evidence to Support Regulato...

Federal Register

Device Consensus Standards Listing

Federal Register notice: FDA publishes modifications to its list of standards FDA recognizes for use in premarket reviews: Modifications to the List o...

Human Drugs

RWD Regulatory Decision Guidance

FDA issues a draft guidance on using real-world data and evidence to support NDA and BLA decisions.

Human Drugs

CMC Postapproval Manufacturing Guidance

FDA publishes a guidance on the types of changes to an approved BLA to be documented in an annual report.

Medical Devices

Entellus Medical, Doctor, Resolve False Claims Suit

The Justice Department says Entellus Medical and the owner of a Georgia surgical practice will pay $4.2 million to resolve a whistleblowers False Clai...

Human Drugs

CDER Web-Based Meeting MAPP

A CDER Manual of Policies and Procedures outlines policies and responsibilities of meeting participants when they are working remotely and using Web-b...

Human Drugs

Clinical Hold Lifted on Aprea Therapeutics

FDA lifts a clinical hold against an Aprea Therapeutics clinical trial evaluating the combination of its lead compound, eprenetapopt, with acalabrutin...

Biologics

EUA Expanded for Pfizer Covid Vaccine

FDA grants Pfizer and BioNTech an expanded emergency use authorization for their Covid-19 vaccine booster to include individuals 16 years of age and o...

Human Drugs

Synaptent Marketing Unapproved New Drugs: FDA

FDA warns Chicago-based Synaptent it is marketing unapproved and misbranded new drugs as dietary supplements.

Human Drugs

8 Observations in Dr. Reddys FDA-483

FDA releases the FDA-483 with eight observations issued following an inspection at a Dr. Reddys sterile drug manufacturing facility in India.