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Human Drugs

Value of FDA Accelerated Approval Not Proven: Researchers

Researchers say CMS too often pays for drugs that received FDA accelerated approval but did not confirm a clinical benefit.

Human Drugs

FDA Removes Hold on Legend CAR-T Therapy

FDA removes a clinical hold against a Legend Biotech Phase 1 clinical trial of LB1901, an investigational autologous chimeric antigen receptor T-cell ...

Medical Devices

Stryker Q Guidance for Computer-assisted Surgery Cleared

FDA clears a Stryker 510(k) for its Q Guidance System for advanced planning and intraoperative guidance during open or percutaneous computer-assisted ...

Medical Devices

FDA Denies Most Parts of 4 Dental Amalgam Petitions

FDA denies most elements in four Consumers for Dental Choice petitions seeking additional agency actions to stop or reduce amalgam use in dentistry.

Human Drugs

Esophageal Cancer Indication for BMS Opdivo

FDA approves two indications involving Bristol-Myers Squibbs Opdivo in combination with other drugs for some esophageal cancers.

Human Drugs

Clinical Hold on Sanofi OTC Cialis Trial

FDA places a clinical hold on a Sanofi actual use trial to support its planned Rx-to-OTC switch for Cialis (tadalafil), which it licensed from Eli Lil...

Human Drugs

BioMarin Resubmitting Hemophilia A BLA in September

BioMarin Pharmaceutical plans to resubmit a BLA for valoctocogene roxaparvovec, a gene therapy for severe hemophilia A, by the end of September that w...

Human Drugs

FDA Extends Review of Multiple Sclerosis Therapy

FDA extends by three months its review of a TG Therapeutics BLA for ublituximab, indicated for treating patients with relapsing forms of multiple scle...

Federal Register

Panel to Discuss Xenotransplantation Regulatory Issues

Federal Register notice: FDA announces a 6/30 Cellular, Tissue, and Gene Therapies Advisory Committee meeting to discuss the current regulatory expect...

Federal Register

Panel to Discuss Novavax Covid-19 Vaccine

Federal Register notice: FDA announces a 6/7 Vaccines and Related Biological Products Advisory Committee meeting to review Novavaxs Covid-19 vaccine a...