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Human Drugs

Wells Pharma Hit With 483 After Inspection

FDA issues Wells Pharma (Houston, TX) a one-item Form FDA-483 after a 6/2021 inspection at the drug outsourcing facility.

Human Drugs

Guide on Mitigating Primate Supply Contraints

FDA releases a final guidance entitled Nonclinical Considerations for Mitigating Nonhuman Primate Supply Constraints Arising from the Covid-19 Pandemi...

Federal Register

Immunogenicity Drug Labeling Guidance

Federal Register notice: FDA makes available a draft guidance entitled Immunogenicity Information in Human Prescription Therapeutic Protein and Select...

Federal Register

Guide on Population Pharmacokinetics

Federal Register notice: FDA makes available a final guidance entitled Population Pharmacokinetics.

Federal Register

Guide on Drug Pressor Effects

Federal Register notice: FDA makes available a revised draft guidance entitled Assessment of Pressor Effects of Drugs.

Federal Register

Class 2 for Apple Irregular Heart Rhythm Monitor

Federal Register notice: FDA classifies Apples photoplethysmograph analysis software for over-the-counter use into medical device Class 2.

Human Drugs

Cytokinetics NDA for Heart Failure Drug

FDA accepts for review a Cytokinetics NDA for omecamtiv mecarbil, an investigational, selective, small molecule cardiac myosin activator for treating ...

Human Drugs

Califf Vows Tough Accelerated Approval Enforcement

In a move to gain Senate backing of his FDA commissioner nomination, Robert Califf promises once in office to crack down on drug companies that gain a...

Clinical Trial Diversity Bill Introduced

Three Congressional representatives introduce bipartisan legislation intended to increase diversity in clinical trials.

Human Drugs

Pfizer, Ionis Bail on Vupanorsen Development

Pfizer and Ionis say they are discontinuing a development program for vupanorsen for potential cardiovascular risk reduction.