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Human Drugs

FDA Finalizes PLAIR Guidance

FDA publishes a finalized 2013 draft guidance on pre-launch activities importation requests.

Federal Register

Guide on Oncology Expansion Cohorts

Federal Register notice: FDA makes available a final guidance entitled Expansion Cohorts: Use in First-in-Human Clinical Trials to Expedite Developmen...

Human Drugs

FDA Hold on Celyad Oncology Trial

FDA puts a clinical hold on a Ceylad Oncology Phase 1b trial due to insufficient information to assess the risk to study subjects.

Former FDAer Wants Freeze on Russian Applications

Former FDAer Timothy Cote asks FDA to suspend regulatory actions on all requests it has from Russian pharmaceutical and medical device companies.

Human Drugs

FDA-483 from OSRX Inspection

FDA releases the FDA-483 with one observation issued following an inspection at OSRX, a Missoula, MT, sterile drug compounder.

Human Drugs

2nd Patient-Focused Drug Development Guidance

FDA publishes the second in a planned series of four methodological guidances on patient-focused drug development.

Federal Register

Bone Fixation Screw Sleeve Class 2

Federal Register notice: FDA classifies the screw sleeve bone fixation device into Class 2.

Medical Devices

Guidance on CDRHs Appeals Processes

FDA releases final guidance on CDRHs Appeals Processes that describes the processes available to stakeholders to seek supervisory review of decisions ...

Medical Devices

Revoke Eye-Sync 510(k) Indication: Pink Concussions

Pink Concussions asks FDA to revoke clearance for the SyncThink Eye-Sync as an aid in diagnosing concussions because it does not add any value to a sy...

FDA Still Not Releasing Drug NCT Numbers

Attorney and data scientist Bradley Thompson says FDA hasnt responded to his request for information on when it will start releasing NCT numbers assoc...