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Human Drugs

Repeat Violations at 3 Ultra Seal Facilities

FDA warns New Paltz-NY headquartered Ultra Seal Corp. about CGMP violations at its headquarters and two other drug manufacturing facilities in the sta...

Human Drugs

FDA Finds Repeat Violations at Yusef Labs

FDA warns Clearfield, UT-based Yusef Manufacturing Laboratories about multiple repeated CGMP violations in its production of finished drugs.

Human Drugs

Veru Reports Positive Data from Covid Therapy Trial

Veru Inc. announces positive efficacy and safety results from an interim analysis of a Phase 3 Covid-19 clinical trial evaluating oral sabizabulin 9 m...

Medical Devices

2 Performance Based Pathway Guidances

FDA publishes two guidances giving submitters using the 510(k) Safety and Performance Based Pathway for two specific products an option to use perform...

Medical Devices

Estimate Device Malfunction Risk Carefully: Attorney

Attorney Jeffrey Shapiro says companies should be careful when calculating for FDA the risk of a medical device malfunction.

Medical Devices

Total Product Lifecycle in Cyber Guidance

A CDRH official says a new draft cybersecurity guidance has teeth that make it more likely that companies that follow its recommendations will achieve...

Federal Register

FDA Nixes Indication on Securas Copiktra

Federal Register notice: FDA announces that it is withdrawing approval of a Secura Bio indication for Copiktra (duvelisib) for treating relapsed or re...

Biologics

Hold on Covid-19 Vaccine After WHO Inspection

FDA places a clinical hold on an Ocugen Phase 2/3 immuno-bridging and broadening study for its Covid-19 vaccine Covaxin (BBV152) after the World Healt...

Human Drugs

BIMO Metrics Show Major Inspection Declines

FDAs Bioresearch Monitoring Program metrics report for fiscal year (FY) 2021 shows substantially fewer clinical investigator and IRB inspections condu...

Medical Devices

Comments on Discontinuance/Interruption Guidance

Four medical device stakeholders call for changes to an FDA draft guidance on notifying the agency in advance of a public health emergency about devic...