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FDA General

GAO Calls Out Unfinished FDA Inspection Recommendations

The U.S. Government Accountability Office writes HHS about the need for FDA to make it a high priority to act on inspection-related recommendations th...

Medical Devices

Senate Bipartisan Bill on Device Cybersecurity

U.S. Senators Jacky Rosen (D-NV) and Todd Young (R-IN) introduce their bipartisan Strengthening Cybersecurity for Medical Devices Act that would manda...

Human Drugs

FDA Extends Review of Amylyxs ALS Drug

FDA extends the review of an Amylyx Pharmaceuticals NDA for AMX0035 (sodium phenylbutyrate and taurursodiol), for treating amyotrophic lateral scleros...

Medical Devices

New Apyx Renuvion J-Plasma Handpiece Available

FDA says it has approved a new dermal handpiece for the Apyx Renuvion/J-Plasma.

Human Drugs

CFP Acquisitions FDA-483

FDA releases the FDA-483 with five observations from an inspection at Tulsa, OK-based CFP Acquisitions, a sterile drug producer.

Medical Devices

OIG Doesnt Fault a Device Doctor-Distributor

Three Goodwin Procter attorneys describe safeguards that keep a physician-owned distributor of a medical device from facing anti-kickback sanctions.

Biologics

Gamida Cell Completes Rolling BLA for Omidubicel

Gamida Cell completes a rolling BLA submission for omidubicel, indicated for patients with blood cancers in need of stem cell transplant.

Human Drugs

Centessa Scraps Lixivaptan in Kidney Disease

Centessa Pharmaceuticals discontinues its development of lixivaptan for autosomal dominant polycystic kidney disease after due to a questionable safet...

Medical Devices

Illumina Cybersecurity Vulnerability: FDA

FDA says a cybersecurity vulnerability in some Illumina next-generation sequencing instruments could affect patient results.

Biologics

Aeglea Bio Hit With BLA Refusal-to-File Letter

FDA sends Aeglea BioTherapeutics a refusal-to-file letter for its BLA for pegzilarginase, indicated for treating arginase 1 deficiency (ARG1-D), reque...