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Federal Register

Guide on Quantitative Imaging Device Filings

Federal Register notice: FDA makes available a final guidance entitled Technical Performance Assessment of Quantitative Imaging in Radiological Device...

Human Drugs

Central Admixture Pharmacy FDA-483

FDA releases the FDA-483 with six observations from an inspection at Phoenix, AZ-based Central Admixture Pharmacy Services.

Human Drugs

Merck Keytruda sBLA for Non-small Cell Lung Cancer

FDA accepts for review a Merck supplemental BLA seeking approval for Keytruda (pembrolizumab) for the adjuvant treatment of patients with Stage IB, II...

Human Drugs

Stakeholders Seek Changes in CAR-T Draft Guidance

Five stakeholders recommend changes and clarifications to an FDA draft guidance on CAR-T cell product development.

Biologics

Gene Editing Stakeholder Comments

Six stakeholders provide comments to FDA on the agencys docket on human gene therapy products incorporating human genome editing.

Human Drugs

Researchers Confirm Increasing AI/ML Role in Drug Development

CDER researchers describe the increasing use of artificial intelligence/machine learning in drug development regulatory submissions.

Human Drugs

CDER Caught Up on Domestic Pre-approval Inspections: Cavazzoni

CDER director Patrizia Cavazzoni puts a positive spin on drug inspections, user fee goals, and enforcement and compliance activities, notwithstanding ...

Human Drugs

FDA Approves Rhythm Pharma sNDA for Imcivree

FDA approves a Rhythm Pharmaceuticals supplemental NDA for Imcivree (setmelanotide) injection, indicated for chronic weight management in adult and pe...

Human Drugs

Advisors to Consider Acadias Nuplazid for Alzheimers Psychosis

FDA says its Psychopharmacologic Drugs Advisory Committee will consider whether data from Acadia Pharmaceutical trials support an indication for the c...

Human Drugs

Alston & Bird Attorneys Review PDUFA 7 Provisions

Four Alston & Bird attorneys describe some of the major items in the PDUFA 7 reauthorization legislation that has bipartisan support in both the House...