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Monoclonal Antibody Manufacturing Changes Research

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FDA researchers look at manufacturing changes and comparability assessment of FDA-approved monoclonal antibodies and Fc-fusion pro...

I-Mab Gets Breakthrough for Nephropathy

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FDA grants I-Mab a breakthrough therapy designation for felzartamab, an investigational CD38 antibody for treating primary membran...

House GOPers Concerned About FDA Lab Safety

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Republican members of the House Energy and Commerce Committee express concern about FDA inaction on the safety of agency laborator...

Hold on Nurix B-cell Malignancies Study

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A transition to an improved manufacturing process leads to an FDA partial clinical hold on a Nurix Therapeutics clinical study eva...

Patient Engagement Panel Renewal

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Federal Register notice: FDA renews its Patient Engagement Advisory Committee for an additional two years beyond the charter expir...

FDA Continues Device Supplement Guidance

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FDA says it will continue to exercise enforcement discretion for some supplements to PMAs and HDEs.

FDA OKs Keytruda in Biliary Tract Cancer

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FDA approves Mercks Keytruda (pembrolizumab) for use with gemcitabine and cisplatin for locally advanced unresectable or metastati...

Why Are FDA-483 Observations the Same?

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Former FDAer Steve Lynn asks what the drug industry and regulators can do working together to break the cycle of more than 20 year...

FDA Seeks Nonvoting Device Panel Members

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Federal Register notice: FDA selects interested industry organizations to participate in selecting nonvoting industry representati...

FDA Terminating Winnes Debarment

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Federal Register notice: FDA grants a special termination of the debarment of David Winne due to his cooperation with federal offi...