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Medical Devices

CDRH Says Major Deficiency Letters Now at 81% of PMAs

FDA background materials for a MDUFA 3 quarterly performance meeting covering the first quarter of FY 2017 say that the percentage of PMA originals an...

Human Drugs

CDERs Top Priority is Informatic Process Management: Woodcock

CDER director Janet Woodcock says that implementing informatics process management is the Centers highest priority in 2017.

Human Drugs

FDA Accepts 3 Merck/Pfizer NDAs for Diabetes

FDA accepts for review three Merck and Pfizer NDAs for medicines containing ertugliflozin, an investigational SGLT2 inhibitor under development to hel...

Human Drugs

FDA Accepts PTC NDA Protestֺ Resubmission for Duchenne Drug

FDA accepts for review a PTC Therapeutics NDA that was filed in protest for Translarna (ataluren) for treating nonsense mutation Duchenne muscular dys...

Human Drugs

FDA Lifts Clinical Holds on Seattle Genetics Leukemia Drug

FDA lifts clinical holds against several Seattle Genetics Phase 1 trials of vadastuximab talirine (SGN-CD33A; 33A) in acute myeloid leukemia.

Public Citizen Cautions Congress on Right to Try Bills

Consumer advocacy group Public Citizen urges Congress to reject three right to try bills (S 204, HR 878 and HR 1020) because they would put countless ...

Human Drugs

Former FDA Head McClellan Weighs in on Speedier FDA

Former FDA commissioner Mark McClellan says a speedier FDA review process is unlikely to benefit public health as much as improving product developmen...

Human Drugs

Senators Ask GAO to Probe Orphan Drug Act

Sen. Chuck Grassley (R-IA) expands his inquiry into potential misuses of FDAs orphan drug program in the wake of the agencys recent approval of Marath...

Federal Register

Flonase Not Withdrawn Due to Safety/Effectiveness

Federal Register Notice: FDA determines that GlaxoSmithKlines allergy drug Flonase (fluticasone propionate) nasal spray, 0.05 mg, was not withdrawn fr...

Federal Register

Public Meeting on Autism Drug Development

Federal Register Notice: FDA announces a 5/4 public meeting and an opportunity for public comment on Patient-Focused Drug Development for autism.