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Human Drugs

Industry Comments Seek Changes on Endpoints Guidance

Drug industry comments on a draft guidance about Multiple Endpoints in Clinical Trials seek changes and further clarifications about multiplicity.

Federal Register

FDA Eliminates Regional Director Positions

Federal Register final rule technical amendment: FDA makes revisions to Chapter I of its regulations to eliminate the position of regional food and dr...

Medical Devices

FDA Clears Toshiba Medical Ultrasound

FDA clears a Toshiba Medical 510(k) for the Aplio i900 ultrasound platform.

Human Drugs

AstraZeneca Gets 2nd Complete Response on ZS-9

FDA issues AstraZeneca a second complete response letter on its NDA for ZS-9 (sodium zirconium cyclosilicate), indicated for treating hyperkalemia (hi...

Medical Devices

FDA Clears DJO Global Hip Revision Device

FDA clears a DJO Global 510(k) for its Exprt Revision Hip, which claims an 80-90% reduction in instruments from competitors.

Human Drugs

Notes for Companies Using Foreign Manufacturing Sites

Attorney Alan Minsk suggests ways companies should respond to FDA inspections at foreign drug manufacturing facilities.

Federal Register

Sarcopenia Meeting Location Changed

Federal Register notice: FDA corrects a 12/15/2016 notice entitled Public Meeting on Patient-Focused Drug Development for Sarcopenia to reflect a chan...

FDA General

Constituencies Oppose Trumps Proposed FDA Budget Cuts

FDA constituencies push back on the Trump Administrations fiscal year 2018 budget blueprint that calls on regulated industry to pay twice as much in u...

FDA General

FDA Dissolves Regional Food, Drug Director Positions

FDA says it is changing its regulations to replace references to Regional Food and Drug Director positions with references to Office of Regulatory Aff...

Federal Register

Cyanocobalamin Not Withdraw Over Safety/Effectiveness

Federal Register notice: FDA determines that cyanocobalamin injection, 1 milligram per milliliter in a 10 milliliter vial, was not withdrawn for reaso...