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Medical Devices

Medtronic HeartWare Splice Kit Recall is Class 1: FDA

FDA says Medtronics recall of a HeartWare driveline splice kit due to a design defect that could lead to an interrupted electrical connection to a ven...

Human Drugs

FDA Approves Designations for 3 Additional Sangamo Products

FDA grants special regulatory designations to three additional Sangamo Therapeutics products.

Human Drugs

Apotex Wants Neulasta Biosimilar Requirements

Apotex asks FDA to set specific requirements for biosimilar applicants referencing Amgens Neulasta.

Medical Devices

FDA Clears Interscope EndoRotor System

FDA clears an Interscope 510(k) for the EndoRotor System for use in gastroenterology and colorectal surgery.

Human Drugs

FDA OKs Phase 3 Trial for Soligenixs Dusquetide

FDA gives Soligenix the green light to advance a pivotal Phase 3 clinical trial evaluating SGX942 (dusquetide) for treating oral mucositis in head and...

Human Drugs

IND Approved for ZioPharm CAR-T Therapy in Leukemia Patients

FDA approves an investigator-initiated IND to begin a Phase 1 trial involving ZioPharm Oncologys CD33-specific CAR-T therapy for relapsed or refractor...

Human Drugs

Patient Groups Expanded Access Principles

Seven patient advocacy groups issue principles they want to see followed in any changes to the compassionate use process.

Human Drugs

Aurobindo Pharma FDA-483 Released

FDA releases an FDA-483 with six observations from an agency inspection at Indias Aurobindo Pharma.

Human Drugs

FDA Seeks More Data on Intra-Cellular Schizophrenia Drug

FDA tells Intra-Cellular Therapies that it has concerns with certain findings observed in nonclinical animal toxicology studies involving ITI-007 (lum...

Medical Devices

Medtronic Resolute Onyx Drug-eluting Stent Approved

FDA approves a Medtronic PMA for the Resolute Onyx Drug-Eluting Stent (DES) in 4.5 mm and 5.0 mm sizes to treat patients with large coronary anatomies...