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Human Drugs

Reject Mayne Pharma Doryx MPC Petition: Mylan

Mylan asks FDA to deny a Mayne Pharma petition seeking to impose additional requirements on ANDAs referencing Maynes Doryx MPC delayed-release tablets...

Federal Register

Technical Amendment to Civil Money Penalty Rule

Federal Register notice of technical amendment: FDA amends a final rule on Civil Money Penalty Definitions.

Human Drugs

BLA Assessment Roles Clarified

CDER issues a MAPP clarifying roles and responsibilities of the Office of Biotechnology Products and the Office of Process and Facilities in assessing...

Federal Register

ICH Revised Guide on CTD Efficacy

Federal Register notice: FDA announces the availability of a guidance on M4E(R2): The CTD Efficacy, an International Council for Harmonization revise...

Human Drugs

Celgene Agrees to Pay $280 Million Over Promotion Violations

Celgene agrees to pay $280 million to settle a False Claims Act suit related to the promotion of two cancer treatment drugs for unapproved uses.

Human Drugs

FDA Seeks Another Trial on Eagle Pharmas Ryanodex

FDA sends Eagle Pharmaceuticals a complete response letter on its 505(b)(2) NDA for Ryanodex (dantrolene sodium) for treating exertional heat stroke.

Human Drugs

11 Violations in Bella Pharmaceuticals FDA-483

FDA releases the FDA-483 with 11 observations from an inspection at Bella Pharmaceuticals.

Medical Devices

QS Violations in Whitehall Medical Device Inspection

FDA warns Whitehall/Division of Acorn Engineering about Quality System and Medical Device Reporting violations in its manufacturing of whirlpool immer...

Human Drugs

Eisai Files sNDA for Lenvima

Eisai files a supplemental NDA for the first-line use of Lenvima (lenvatinib), a multiple receptor tyrosine kinase inhibitor for treating patients wit...

Human Drugs

Significant Violations at Sage Products

FDA warns Sage Products about CGMP violations in its manufacturing of finished pharmaceuticals.