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Human Drugs

Surrogate Marker Treatment Effects Can Vary: Study

Researchers say that pivotal trials based on non-continuous surrogate markers often exaggerate treatment effects.

Combination Product Postmarketing Reporting

FDA releases a draft guidance and in-effect compliance guide on postmarket safety reporting for combination products.

Human Drugs

CGMP Deviations at Malladi Drugs

FDA warns Indias Malladi Drugs & Pharmaceuticals about CGMP deviations in its manufacturing of API.

Human Drugs

Researchers Make Case for Some Off-Patent Drug Imports

Researchers from three universities say it should be possible to design a safe system through which Americans could obtain off-patent drugs manufactur...

Marketing

Drug Companies See Coupons as Financial Risk

MarketWatch says drug companies fear that new co-pay accumulator initiatives will lower their sales as patients look for lower-cost alternatives.

Human Drugs

Court Allows Amended Proscar Complaint

A Massachusetts state court says a plaintiff may amend one element of his complaint against Merck alleging intentional failure to update the Proscar l...

Medical Devices

FDA Clears Restoration Robotics Hair Restoration Device

FDA clears a Restoration Robotics 510(k) to expand the Artas hair restoration technology to include robotic implantation.

Human Drugs

Pfizer/Astellas sNDA Accepted for Xtandi

FDA accepts for priority review a Pfizer and Astellas Pharma supplemental NDA for Xtandi (enzalutamide) for an expanded indication to include men with...

Medical Devices

Exactech 510(k) Cleared for Novation XLE Hip Liners

Exactech gains 510(k) clearance to market the Novation XLE Vitamin E acetabular polyethylene liners for hip replacement surgery.

Human Drugs

Trump Threatens to Sue Pharma Companies Over Opioid Crisis

President Trump warns pharmaceutical companies marketing opioid and other addictive pain killers that the Department of Justice is looking very seriou...