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Medical Devices

FDA Clears K2Ms Ozark Cervical Plate Systems

FDA clears a K2M Group Holdings 510(k) for its Ozark Cervical Plate Systems for anterior screw fixation to the cervical spine in patients with degener...

Medical Devices

Changes in Sequencing Guidances Explained

A CDRH Webinar reviews changes made to next generation sequencing guidances.

Human Drugs

AAM Wants Case-by-Case 505(b)(2) Determinations

The Association for Accessible Medicines urges FDA to adopt a case-by-case approach in determining whether a 505(b(2) biologic should be deemed to be ...

Human Drugs

FDA Priority Review for Pfizer Breast Cancer Therapy

FDA accepts for priority review a Pfizer NDA for talazoparib for use in patients with germline (inherited) BRCA-mutated (gBRCAm), HER2-negative locall...

Human Drugs

Orphan Drug Status for Ironwoods Olinciguat

FDA grants Ironwood Pharmaceuticals an orphan drug designation for olinciguat (IW-1701) for treating patients with sickle cell disease.

Human Drugs

Former FDAer John Jenkins Joins Corbus Board

Former Office of New Drugs director John Jenkins joins the Corbus Pharmaceuticals board.

Federal Register

Sun Pharma Not Withdrawing Benazepril HCl/Hydrochlorothiazide

Federal Register notice: FDA corrects a 2/23 notice announcing that Sun Pharmaceutical Industries asked to withdraw its generic benazepril hydrochlori...

Human Drugs

FDA Nixes Mylan/Biocon Lantus Biosimilar

FDA rejects Mylan/Biocons biosimilar application for a Lantus follow-on due to manufacturing site questions.

Human Drugs

Injunction Sought Against Innovative BioDefense

FDA files a complaint seeking a permanent injunction against Innovative BioDefense (Lake Forest, CA) and president/CEO Colette Cozean to prohibit them...

Human Drugs

Fixed-Combination Antiretroviral Drug Waiver Guidance

FDA issues a guidance on circumstances in which an NDA applicant may be eligible for a barrier-to-innovation PDUFA waiver for fixed-combination and si...