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Human Drugs

AbbVie sNDA Accepted for Imbruvica

FDA accepts for priority review an AbbVie supplemental NDA for Imbruvica (ibrutinib) in combination with obinutuzumab (Gazyva) in previously untreated...

Federal Register

Draft Guide on Hematologic Malignancies Drug Development

Federal Register notice: FDA makes available a draft guidance entitled Hematologic Malignancies: Regulatory Considerations for Use of Minimal Residual...

Federal Register

Guide on Targeted Therapies

Federal Register notice: FDA makes available a final guidance entitled Developing Targeted Therapies in Low-Frequency Molecular Subsets of a Disease....

Human Drugs

Clinical Investigator Violations Cited

FDA warns California doctor Ignatius Godoy about violations in his role as clinical investigator in a pediatric flu vaccine study.

Medical Devices

Regulatory Considerations for Dialysis Catheters

CDRH participates in a Kidney Health Initiative workgroup to explain regulatory considerations for central venous catheters for hemodialysis.

Marketing

FDA Wants Comments on Proposed DTC Study

FDA asks for comments on proposed research looking at how consumers respond to disease awareness communications that accompany television direct-to-co...

Marketing

DTC Ad Efficacy and Risk Info Guidance

FDA issues a draft guidance with recommendations for how companies can present quantitative efficacy and risk information in DTC human and animal drug...

Human Drugs

Pfizers Talzenna OKd for Breast Cancer

FDA approves Pfizers Talzenna (talazoparib), a poly (ADP-ribose) polymerase inhibitor for certain patients with locally advanced or metastatic breast ...

3-Factor Approach for Product Communications: FDA

FDA outlines a three-factor approach it uses to evaluate whether a drug- or device-related product communication is consistent with the products agenc...

Medical Devices

FDA Rejects TearLab 510(k) for Dry Eye Test

FDA rejects a TearLab Corp. 510(k) for its TearLab Discovery MMP-9 test for dry eye disease.