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FDA General

Latest FDA Warning Letters

FDA releases its latest batch of Warning Letters that include The Delano Co. and Mylan Pharmaceuticals.

Human Drugs

Drug Post-Approval Change Guidance Comments

Six drug company stakeholders ask FDA for changes to an agency draft guidance on post-approval changes to drug substances.

Human Drugs

Restrictions Sought on Zelnorm sNDA

Hyman, Phelps & McNamara asks FDA not to approve a Zelnorm sNDA without substantial evidence of safety and efficacy under currently applicable standar...

Human Drugs

Synaptive Medical Recalls BrightMatter Guide

Synaptive Medical recalls its BrightMatter Guide with SurfaceTrace Registration due to a software defect that could potentially result in serious or l...

Human Drugs

QS Issues at Mylan Morgantown Plant

FDA warns Mylan about CGMP violations at its Morgantown, WV, drug manufacturing facility.

Human Drugs

Clinical Hold Placed on Zafgen Diabetes Therapy

FDA places a clinical hold on a Zafgen clinical trial of ZGN-1061, the companys second-generation, investigational MetAP2 inhibitor currently in devel...

Medical Devices

Discussion Document on Patient Engagement in Device Trials

FDA releases a discussion document on patient engagement in the medical device clinical trial process as a follow-up to its 10/2017 Patient Engagement...

Medical Devices

FDA Plans to Retire Outdated 510(k) Predicates

FDA says it is examining ways to modernize the medical device 510(k) process by relying more on a review that weighs new technologies that improve dev...

Human Drugs

FDA-483 Issued After Cantrell Drug Co. Inspection

FDA issues a Form FDA-483 after an August inspection of a Cantrell Drug Co. outsourcing facility in Little Rock, AR.

Human Drugs

FDA OKs Genentechs ACTPen Autoinjector

FDA approves Genentechs ACTPen 162 mg/0.9 mL, a single-dose prefilled autoinjector for Actemra (tocilizumab) as an additional formulation for certain ...