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Human Drugs

Macleods Pharm Recalls 1 Lot of Hypertension Drug

Macleods Pharmaceuticals recalls one lot of losartan potassium/hydrochlorothiazide 100mg/25mg combination tablets due to an impurity level concern.

Human Drugs

Safety Alert on Pfizers Xeljanz

A new FDA safety alert warns about Pfizers tofacitinib (Xeljanz, Xeljanz XR) after a clinical trial found an increased risk of blood clots in the lung...

Federal Register

Latest Federal Register Notices

FDA Review posts the Federal Register notices for the week ending 2/22/2019.

FDA General

Product Approval Summaries

FDA Review posts product approval summaries for the week ending 2/22/2019.

Medical Devices

Guide on Implanted Brain-Computer Interface Devices

FDA posts a draft guidance entitled Implanted Brain-Computer Interface (BCI) 1 Devices for Patients with Paralysis or Amputation Non-clinical Testing...

Human Drugs

Orphan Status for Imbrium Biliary Cancer Drug

FDA grants Imbrium Therapeutics an orphan drug designation for its investigational drug etoposide toniribate, intended for treating relapsed refractor...

Human Drugs

Alexion Files sBLA for Soliris Expanded Use

FDA accepts for review an Alexion Pharmaceuticals supplemental BLA for the use of Soliris (eculizumab) in treating certain patients with neuromyelitis...

Medical Devices

ICU Medical Recalls ChemoLock Vial Spikes

ICU Medical begins a Class 1 recall of one lot of ChemoLock Vial Spikes, 20mm due to the potential for plastic particles to break off the protective c...

Medical Devices

Biotronik PMA Approved for Orsiro Drug-eluting Stent

FDA approves a Biotronik PMA for its Orsiro drug-eluting stent system.

Human Drugs

Gottlieb, Woodcock Reassure on Generic Drug Quality

FDA commissioner Scott Gottlieb and CDER director Janet Woodcock defend the agencys oversight of the generic drug industry to quash any doubt that gen...