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Biologics

Lot Release Protocol Submission Guidance

CBER issues a guidance to help biological product manufacturers submit lot release protocols in electronic format.

Human Drugs

1,021 ANDA Approvals in 2018: Report

The Office of Generic Drugs annual report shows that 1,021 ANDAs were approved or tentatively approved in 2018.

Federal Register

National Center for Toxicological Research Advisory Committee

Federal Register notice: FDA announces a 3/19-20 meeting of the National Center for Toxicological Researchs Science Advisory Board.

Medical Devices

FDA Tracking Sterigenics Closure Impact

CDRH says it is evaluating whether any medical device supply issues will result from the closing of the Sterigenics Willowbrook, IL, product steriliza...

Medical Devices

Medtronic Accurian RF Ablation Platform Cleared

FDA clears a Medtronic 510(k) for the Accurian RF ablation platform for use in radio frequency ablation of nerve tissues.

Human Drugs

Bayer Completes Cancer Drug Rolling NDA

Bayer completes submission of a rolling NDA for its investigational prostate cancer drug darolutamide.

Human Drugs

FDA Refusal to File Letter on Adamis ED Drug

FDA issues Adamis Pharmaceuticals a Refusal to File letter on an NDA for its sublingual tadalafil product, indicated for treating erectile dysfunction...

Human Drugs

CGMP Issues at Spains Proandre SL

FDA warns Spains Proandre SL about CGMP violations in its production of drugs.

Human Drugs

Pure Source Inspection Finds CGMP Violations

FDA warns Pure Source about CGMP violations in its work as a contract manufacturer of homeopathic drugs.

Human Drugs

Gottlieb: FDA Requiring Long-term Studies on Opioids

Following a critical CBS 60 Minutes report that claimed FDA ignited the current opioid crisis, commissioner Scott Gottlieb says the agency will requir...