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Human Drugs

Panel Deadlocks on Lexicon/Sanofi Diabetes Drug

FDAs Endocrinologic and Metabolic Drugs Advisory Committee votes 8 to 8 on whether to recommend approval for Lexicon Pharmaceuticals Inc and Sanofis s...

Human Drugs

Accelerated Approval Drug Labeling Guidance

FDA issues a guidance to help drug and biological product applicants develop the Indications and Usage section of labeling for products approved under...

Human Drugs

Draft ICH Nonclinical Safety Test Guidance

FDA releases a draft International Council for Harmonization guidance on nonclinical safety testing of pediatric drugs.

Medical Devices

Safety, Performance Based Pathway Guidance

FDA releases a guidance explaining the agencys Safety and Performance Based Pathway as an alternative approach for 510(k) submissions.

Biologics

FDAs Options Against Violative Stem Cell Clinics

Attorney Mark Schwartz explores enforcement options open to FDA following expiration of the enforcement discretion period for stem cell facilities it ...

FDA General

CBS Profiles Furloughed FDA Food Inspector

CBS News profiles an FDA food safety investigator whose care for his autistic son is threatened because he has been furloughed from the agency.

Medical Devices

23andMe Colorectal Cancer Report Cleared

FDA clears a 23andMe 510(k) for the MUTYH-Associated Polyposis report, a genetic health risk report on a hereditary colorectal cancer syndrome.

Human Drugs

Albireo Gains Orphan Status for Liver Disease Drug

FDA grants Albireo Pharma an orphan drug designation for A4250, an ileal bile acid transporter inhibitor for treating biliary atresia.

Human Drugs

More Patient-Reported Outcome Bias Study Needed: FDA

FDA researchers say efforts should be made to understand and account for potential bias in cancer drug patient-reported outcomes.

FDA General

Product Approval Summaries

FDA Review posts product approval summaries for the week ending 1/18/2019.