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Human Drugs

Review iPLEDGE Isotretinoin Fetal Defects: Researchers

Researchers call for reevaluation of the iPLEDGE isotretinoin program and exploration of new approaches to lower fetal exposure to the drug.

Medical Devices

Pear Therapeutics Seeks Somryst Marketing OK

Pear Therapeutics says it filed a request for marketing authorization with FDA for its Somryst prescription digital therapeutic to treat chronic insom...

Human Drugs

Value of Risk-Based Quality Management

Presenters at an FDA/Duke Margolis Center conference discuss FDA interest in risk-based quality management, including clinical trial monitoring.

Human Drugs

FDA Accepts Allergans Bimatoprost SR NDA

FDA is expected to act by mid-2020 on an Allergan NDA for Bimatoprost SR indicated for reducing intraocular pressure in patients with open-angle glauc...

Human Drugs

FY 2018 OGD Research Grants

The Office of Generic Drugs science and research report for FY 2018 says 13 research contracts and 11 grants for innovative research were funded.

Federal Register

Info Collection Extension for CDRH Appeals Process

Federal Register notice: FDA submits to OMB an information collection extension for Center for Devices and Radiological Health Appeals Processes.

Human Drugs

Novartis Reserves $700 Million to Settle Whistleblower Suit

Novartis says it has reserved about $700 million to settle U.S. government allegations that it illegally enticed physicians to prescribe its drugs.

Human Drugs

Horizon NDA Accepted for New Procysbi Dosage Form

FDA accepts for review a Horizon Therapeutics NDA for a new dosage form for Procysbi (cysteamine bitartrate) delayed-release oral granules in packets...

FDA General

Consent Decree Entered Against J and L Grocery

An Arkansas federal court orders J and L Grocery (Alma, AR) to stop distributing drug products, medical devices, cosmetics and food until the company ...

Human Drugs

62% of FDA-approved Biologics Have Boxed Warnings

A Milwaukee Journal Sentinel investigative report says 62% of biologics approved by FDA carry a Boxed Warning, much higher than the percentage for new...