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Human Drugs

Senators Question HHS Oversight of TrumpRx Platform

A group of Democratic senators ask HHS Office of Inspector General to clarify how it will oversee direct-to-consumer prescription drug sales tied to t...

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Human Drugs

FDA Releases Corrected Rejection Letter for Corcept NDA

FDA releases a corrected version of a 12/30 Complete Response Letter issued to Corcept Therapeutics, indicating that the agency had repeatedly warned ...

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Human Drugs

Ultragenyx Resubmits BLA for Gene Therapy

Ultragenyx Pharmaceutical resubmits a BLA seeking accelerated approval for UX111, an AAV9 gene therapy for the treatment of Sanfilippo syndrome Type A...

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Human Drugs

Elevar Submits Lirafugratinib NDA for Bile Duct Cancer

Elevar Therapeutics files an NDA for lirafugratinib as a second-line treatment for patients with cholangiocarcinoma whose tumors harbor FGFR2 fusions ...

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Human Drugs

Sen. Scott Bill to Require Country-of-Origin on Rx Labels

Sen. Rick Scott (R-FL) introduces legislation that would require prescription drug labels in the U.S. to disclose where drugs and their active pharmac...

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Human Drugs

FDA Approves Yuvezzi Combination Eye Drop for Presbyopia

FDA approves Tenpoint Therapeutics Yuvezzi as the only combination eye drop approved to treat presbyopia in adults.

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Medical Devices

Agency Clarifies Clinical Decision Support Software

FDA posts an updated guidance clarifying when clinical decision support software functions fall outside the definition of a regulated medical device.

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Human Drugs

FDA Staffing Shortages are Lengthening Trial Planning

An industry consultant says reduced FDA staffing levels and high turnover are extending regulatory timelines and forcing drug developers to invest mor...

Biologics

Kennedy Ally Says Makary Blocking Covid Shot Withdrawal

Axios reports that the vice chair of the CDC Advisory Committee on Immunization Practices says the Pfizer and Moderna Covid mRNA vaccines should be re...

Medical Devices

FDA Annual Report on CDRH International Harmonization

CDRH reports on its 2025 MDUFA 5 activities to promote international harmonization.