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Human Drugs

Allergan sBLAs for Pediatric Limb Spasticity

FDA accepts two Allergan supplemental BLAs to expand its Botox (onabotulinumtoxin A)label for treating pediatric patients with upper and lower limb sp...

Human Drugs

Rapastinel Phase 3 Trials Missed Endpoints

Allergan says Phase 3 trials of its rapastinel as an adjunctive therapy for major depressive disorder failed to meet primary and key secondary endpoin...

Human Drugs

Genentech sNDA for Xofluza Expanded Use

FDA accepts for review a Genentech supplemental NDA for Xofluza (baloxavir marboxil) as a single-dose, oral treatment for people at high risk of compl...

Medical Devices

Zoll LifeVest Defibrillator Software Update

FDA updates a safety alert that warned health professionals about Zoll Medicals Zoll LifeVest 4000 Wearable Cardioverter Defibrillator due to concerns...

Federal Register

510(k) Exemption Proposed for Flow Cytometer Instruments

Federal Register notice: FDA seeks comments on its announced intention to exempt certain flow cytometer instruments from premarket notification requir...

Human Drugs

Better Non-efficacy Benefit Communication Needed: Analysis

Researchers say drug sponsors and FDA can do a better job of communicating non-efficacy benefits arising from non-inferiority trials.

Medical Devices

CurvaFix Pelvic Fracture Rodscrew Cleared

FDA clears a CurvaFix 510(k) for the CurvaFix Intramedullary Rodscrew for use in pelvic trauma surgery.

Medical Devices

FDA Clears GEM Premier ChemSTAT IVD

FDA clears an Instrumentation Laboratory 510(k) for the GEM Premier ChemSTAT in vitro diagnostic analyzer with Intelligent Quality Management.

Human Drugs

Janssens Breakthrough Antidepressant Gains Green Light

FDA approves a Janssen Pharmaceuticals NDA for Spravato (esketamine) nasal spray, in conjunction with an oral antidepressant, for treating depression ...

Human Drugs

Questions Aired About CanaRx Warning Letter

American local governments say they plan to continue using CanaRx to import drugs for their employees despite an FDA Warning Letter issued to the onli...