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Federal Register

Clinical Trial Enrichment Strategies Guide

Federal Register notice: FDA makes available a final guidance entitled Enrichment Strategies for Clinical Trials to Support Demonstration of Effective...

Federal Register

Guide on Hematologic Disorders Drug Development

Federal Register notice: FDA makes available a final guidance entitled Severely Debilitating or Life-Threatening Hematologic Disorders: Nonclinical De...

Federal Register

Draft Guide on Clinical Trial Sponsor Monitoring

Federal Register notice: FDA makes available a draft guidance entitled A Risk-Based Approach to Monitoring of Clinical Investigations: Questions and A...

Federal Register

Guidance on Animal-sourced Materials in Devices

Federal Register notice: FDA makes available a final guidance on Medical Devices Containing Materials Derived from Animal Sources (Except for In Vitro...

FDA General

What Grounded Boeings and FDA Have in Common

FDA Webview editor Jim Dickinson sees a troubling parallel between the influence Boeing has had at FAA and the same post-Reagan influence that industr...

Medical Devices

Advisory Panel to Mull Device Metal Hypersensitivity

FDA plans an advisory committee meeting to discuss nitinol and other metals in device implants to understand the potential risk for certain patients t...

Medical Devices

FDA Finds Increased Mortality with Paclitaxel Devices

An updated FDA safety alert on paclitaxel-coated products says that a preliminary data review has identified a potentially concerning signal of increa...

Medical Devices

FDA Clears Thornhill Researchs ClearMate

FDA clears a Thornhill Research de novo marketing request for the ClearMate, intended to be used in an emergency room setting to help treat patients s...

Biologics

Spectrum BLA for Rolontis Withdrawn After FDA Request

Spectrum Pharmaceuticals withdraws a BLA for Rolontis (eflapegrastim), a treatment for chemotherapy-induced neutropenia in patients undergoing myelosu...

Risk-Based Investigation Guidance

FDA releases a draft guidance expanding with questions and answers on an earlier guidance on a risk-based approach to clinical trial monitoring.