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Human Drugs

Multiple Violations in Spectrum Laboratory Inspection

FDA warns Spectrum Laboratory Products about CGMP and other violations in its production of API.

Human Drugs

PhRMA on Patient Involvement in Rare Diseases

PhRMA says participation in a 4/29 meeting on incorporating patient experience in drug development for rare diseases shows the need for FDA to have a ...

Human Drugs

Real-World Data, Evidence Guidance Explained

CDER health science policy analyst Lauren Milner explains in a Webinar the reasons for and use of a new draft guidance on submitting documents using r...

Biologics

Accelerated Approval for Genentechs Polivy

FDA grants Genentech accelerated approval on a BLA for Polivy (polatuzumab vedotin-piiq), in combination with the chemotherapy bendamustine and a ritu...

Human Drugs

CDER Sets Up New Drug Compounding Compliance Team

CDERs Office of Compliance sets up a new compounding team with responsibility for the overall management of the agencys drug compounding compliance pr...

Human Drugs

Provention Bio Positive Study in Type 1 Diabetes

Provention Bio says that a recent study showed that a single 14-day course of PRV-031 (teplizumab) significantly delayed the onset and diagnosis of cl...

Federal Register

Comments Extended on Continuous Manufacturing Guide

Federal Register notice: FDA reopens the comment period on a 2/17 Federal Register notice entitled Quality Considerations for Continuous Manufacturing...

Federal Register

PBPK Modeling Workshop Announced

Federal Register notice: FDA announces an 11/18 The public workshop entitled Development of Best Practices in Physiologically Based Pharmacokinetic (P...

Federal Register

Info Collection Extension for Safety Labeling Changes

Federal Register notice: FDA submits to OMB an information collection extension for FDA Safety Labeling Change Implementation of Section 505(o)(4) of...

Human Drugs

Aurobindo Inspection Results in 9-item Form 483

An FDA inspection last month at Aurobindo Pharmas Telangana, India manufacturing facility leads to a nine-observation Form 483.