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Federal Register

FDA Denys Hearing on Vanda Hetlioz Rejection

Federal Register notice: FDA makes available its decision to deny a request for a hearing on a CDER recent refusal to approve a Vanda supplemental NDA...

EIRS/483s

J&J Stops Phase 3 Depression Drug Program

Johnson & Johnson stops its Phase 3 VENTURA development program evaluating aticaprant as an adjunctive treatment for major depressive disorder due to ...

Animal Drugs

FDA Domestic Inspections Fall, Foreign Rise: Study

Consultants from Eliquent Life Sciences say most of FDAs drug inspection-based Warning Letters issued in fiscal year 2024 went to domestic firms, alth...

Biologics

Celltrion BLA for Interchangeable Xolair Biosimilar

FDA approves a Celltrion BLA for Omlyclo, the first interchangeable biosimilar to Genentechs Xolair (omalizumab).

Human Drugs

FDA Nixes Vanda Hetlioz Hearing

FDA denies a hearing on Vandas Hetlioz sNDA and proceeds with its rejection of the filing.

Medical Devices

Nuwellis AquaFlexFlow Recall is Class 1

FDA says a Nuwellis 12/2024 recall of certain lots of its extracorporeal blood circuits is Class 1.

Biologics

FDA OKs Gene Therapy for Retinal Disease

FDA approves a Neurotech Pharmaceuticals BLA for Encelto (revakinagene taroretcel-lwey) for treating macular telangiectasia Type 2 (MacTel), a neurode...

Medical Devices

Micro Therapeutics Recalls Embolization Device

Medtronics Micro Therapeutics unit recalls its Pipeline Vantage Embolization Device with Shield Technology after it determined that the use of the emb...

Human Drugs

FDA OKs Expanded Use of Furoscix

FDA approves a scPharmaceuticals supplemental NDA for Furoscix (furosemide injection) to expand the indication to include treatment of edema in patien...

Human Drugs

Opportunities for Drug Development Dynamic Tools

FDA reports on a 2024 workshop on using dynamic tools to enhance new drug development efficiency.