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Biologics

Janssen Covid Vaccine Trial Paused Over Unexplained Illness

Johnson & Johnson says an unexplained illness in a study participant has temporarily paused dosing in its Janssen Covid-19 vaccine candidate clinical ...

Biologics

Optimal Health Selling Unapproved Cellular Products: FDA

FDA says Optimal Health Stem Cell and Wellness Institute is marketing cellular products to treat several diseases and conditions without an approved B...

Human Drugs

Pfizers Ibrance Misses Endpoint in Breast Cancer Trial

Pfizer and the German Breast Group say a Phase 3 study involving Ibrance (palbociclib) did not meet the primary endpoint of improved invasive disease-...

Medical Devices

CartiHeal Gets Breakthrough Status for Agili-C Implant

FDA grants CartiHeal a breakthrough device designation for the Agili-C implant and its use in treating cartilage lesions in arthritic and non-arthriti...

Human Drugs

Joint Panel Backs Alkermes Antipsychotic

Two FDA advisory committees vote to support approval of an Alkermes NDA for ALKS 3831 (olanzapine/samidorphan), an oral atypical antipsychotic drug ca...

Human Drugs

Edge Pharma Gets 17-page Form 483

An FDA inspection of Colchester, VT-based Edge Pharma ends in a 17-page Form FDA 483 that cites numerous GMP deficiencies.

Federal Register

Meeting on Ranking Animal Antimicrobial Drugs

Federal Register notice: FDA announces 11/16 virtual public meeting entitled Potential Approach for Ranking of Antimicrobial Drugs According to Their ...

Human Drugs

Avenue Gets Complete Response on Pain Drug

FDA issues Avenue Therapeutics a complete response letter due to safety concerns on its NDA for intravenous tramadol, indicated for treating patients ...

Human Drugs

New Formulation for Alexions Ultomiris

FDA approves Alexion Pharmaceuticals Ultomiris (ravulizumab-cwvz) 100 mg/mL, a new dosing formulation for treating adults with paroxysmal nocturnal he...

Medical Devices

FDA Clears GE Ultra Edition for Vivid Ultrasound

FDA clears a GE Healthcare 510(k) for the Ultra Edition package on its Vivid cardiovascular ultrasound systems, which includes new features based on a...