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Human Drugs

Panel Backs Tecentriq Continued Accelerated Approval

An FDA advisory committee votes to recommend the continuance of Genentechs accelerated approval for Tecentriq (atezolizumab) plus nab-paclitaxel for t...

Biologics

FDA Authorizes Parkinsons Stem Cell Trial

FDA says Hope Biosciences Stem Cell Research Foundation can conduct a Phase 2 trial of multiple infusions of stem cells in patients with Parkinsons di...

Human Drugs

Acceleron Failed to Submit Trial Results: FDA

FDA says Acceleron Pharma failed to submit the required dalantercept clinical trial information to ClinicalTrials.gov.

Biologics

Protalix Gets Complete Response on Fabry Therapy

FDA issues Protalix BioTherapeutics a Complete Response Letter for its BLA seeking accelerated approval for pegunigalsidase alfa (PRX102) for treating...

Medical Devices

Pixee Medical 510(k) for Knee Procedures

FDA clears a Pixee Medical 510(k) for its Knee +, a surgical platform designed to assist orthopedic surgeons by providing real-time positioning of ins...

Human Drugs

BsUFA Reauthorization Steering Committee Ground Rules Set

FDA releases summaries from three Biosimilar User Fee reauthorization negotiating sessions.

Human Drugs

Panel Backs Keytruda and Tecentriq in Bladder Cancer

An FDA advisory committee votes to recommend continued accelerated approvals separately for Mercks Keytruda and Genentechs Tecentriq in bladder cancer...

Biologics

Enzyvant Resubmits BLA for Pediatric Congenital Athymia

Enzyvant resubmits a BLA for RVT-802, a tissue-based regenerative therapy designed to treat pediatric congenital athymia.

Human Drugs

Inspection Delay Impacts Sol-Gel NDA Review

A required preapproval inspection delays Sol-Gel Technologies NDA review for Epsolay (benzoyl peroxide) 5% topical cream for treating rosacea inflamma...

Human Drugs

Antisense Oligonucleotide Nonclinical Testing Guidance

FDA publishes a draft guidance on nonclinical information supporting an IND for some antisense oligonucleotides.