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Human Drugs

Strongbridge NDA for Cushings Syndrome

FDA accepts for review a Strongbridge Biopharma NDA for Recorlev (levoketoconazole) for treating endogenous Cushing's syndrome.

Federal Register

Guide on Drug Biopharmaceutics Classification

Federal Register notice: FDA makes available a final guidance entitled M9 Biopharmaceutics Classification System-Based Biowaivers.

Human Drugs

1st Office of Surveillance and Epidemiology Annual Report

The CDER Office of Surveillance and Epidemiology issues its first annual report dealing with four core functions and looking to the future.

Medical Devices

Shuren Sees Hybrid Inspection Program Post Covid

CDRH director Jeff Shuren tells an industry conference that FDA will likely favor a hybrid inspection program going forward in the post-Covid-19 world...

Federal Register

Guide on Drug Statistical Principles for Clinical Trials

Federal Register notice: FDA makes available a final guidance entitled E9(R1) Statistical Principles for Clinical Trials: Addendum: Estimands and Sens...

Human Drugs

Asthma Drug Study Coordinator Indicted

The Justice Department says a federal grand jury indicted a Miami clinical trial coordinator for conspiring to falsify clinical trial data and making ...

Human Drugs

Appeals Court Affirms Dismissal of Lipitor Diabetes Case

The 2nd Circuit Court of Appeals upholds a New York federal courts dismissal of a suit claiming that Pfizer failed to properly warn that its Lipitor c...

Federal Register

Nonclinical Safety Testing Guide for Pediatric Drugs

Federal Register notice: FDA makes available a final guidance entitled S11 Nonclinical Safety Testing in Support of Development of Pediatric Pharmaceu...

Federal Register

Drug Reproductive Toxicity Testing Guide

Federal Register notice: FDA makes available a final guidance entitled S5(R3) Detection of Reproductive and Developmental Toxicity for Human Pharmaceu...

Medical Devices

Medtronic HeartWare HVAD System Recall is Class 1

FDA says the Medtronic recall of its HeartWare HVAD system to update instructions for use and the patient manual due to three issues is Class 1.