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Human Drugs

Final Approval Granted for Astellas Padcev

FDA grants full approval to Astellas Pharma for Padcev (enfortumab vedotin-ejfv), a Nectin-4-directed antibody and microtubule inhibitor conjugate for...

Human Drugs

Catalyst Wants Specific Tests for Some Amifampridine NDAs

Catalyst Pharmaceuticals asks FDA to apply restrictions to the approval of any NDA for an amifampridine drug product intended to treat congenital myas...

Human Drugs

BCC May Contaminate Some Water-Based Drugs: FDA

FDA says manufacturers of non-sterile water-based drugs should take steps to guard against contamination from Burkholderia cepacia.

Federal Register

Regulatory Review Period for Piqray

Federal Register notice: FDA determines for patent extension purposes the regulatory review period for Novartis Piqray (alpelisib), indicated in combi...

Human Drugs

FDA, Biogen Yield to Critics on Alzheimers Label

FDA approves a Biogen labeling amendment that narrows the indication for its controversial Alzheimers therapy Aduhelm (aducanumab).

Medical Devices

FDA Warning on NuVasives Precise Implants

FDA alerts health care providers about potential biocompatibility concerns associated with NuVasive Specialized Orthopedics Precice devices made from ...

Human Drugs

AstraZeneca Asthma Priority BLA Accepted

FDA accepts for priority review an AstraZeneca BLA for tezepelumab for treating asthma.

Medical Devices

Alere Paying $38.75 Million for False Claims Allegations

The Justice Department says Alere and a subsidiary will pay $38.75 million to resolve False Claims Act allegations involving defective INRatio blood c...

Human Drugs

Novartis Resubmits Inclisiran NDA

Novartis resubmits its NDA for inclisiran, resolving FDA manufacturing facility questions raised in a complete response letter.

Medical Devices

Quidel Lyra Covid Assay Recall for False Negative Risk is Class 1: FDA

FDA says a Quidel recall of 18,365 Lyra SARS-CoV-2 assay kits due to the potential for false-negative results is Class 1.