Federal Register Notice: FDA is making available a guidance, Small Entities Compliance Guide for Renderers — Substances Prohibited From Use in Animal Food or Feed. It intends to help renderers in complying with the requirements of the 4/25 final rule prohibiting the use of certain cattle origin materials in the food or feed of all animals in order to strengthen existing safeguards to prevent the spread of bovine spongiform encephalopathy (BSE) in U.S. cattle and to reduce the risk of human exposure to the BSE agent. To download this guidance, click here. To view this notice, click here.